Follow Us

Oct-4 [Polyclonal]

Ref: AP10423 - Clone: Polyclonal - Host: Rabbit - Method: P - Format: Ready to use
DS  Imagen 1   MSDS  Imagen 2
Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
Oct-4 (Octamer-binding transcription factor 4) is a transcription factor with a central function in embryogenesis. The protein is important for maintaining the pluripotency of embryonic stem cells and primordial germ cells. Oct-4 is also known as Oct-3, OTF3, and POU5F1 (POU domain class 5 transcription factor 1). Oct-4 is a characteristic marker molecule of embryonic stem cells. Many current publications describe that the immunohistochemical staining of this protein is useful to detect metastatic germ cell tumours. Additionally, it was shown that Oct-4 is superior to other markers because of its high specificity and sensitivity. IGCNU (Intratubular germ cell neoplasia, unspecified type), seminomas, embryonal carcinomas, germinomas, and dysgerminomas are consistently positive for Oct-4.

Polyclonal
Isotype: IgG
Immunogen: Synthetic KLH-conjugated peptide according to the amino acid residues 300 to the C-terminus of human Oct-4.
Staining pattern: Nuclear.
Positive control: Tissue sample from seminoma.

APPLICATIONS:
This antibody is designed for the specific localization of human Oct-4 using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
The antibody is useful for the detection of metastatic germ cell tumors.

Reviw on bokmaker Number 1 in uk http://w.artbetting.net/ William Hill
Full Reviw on best bokmaker - Ladbrokes http://l.artbetting.net/ full information
Play Casino Bet365 read more.

CookiesAccept

NOTE! This site uses cookies and similar technologies.

If you not change browser settings, you agree to it.

I understand
Ranking bookmakers sites