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L1-CAM (Neuronal Marker) [UJ127]

Ref: AP10409C - Clone: UJ127 - Host: Mouse - Method: P - Format: Concentrated
DS  Imagen 1   MSDS  Imagen 2
Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Clone: UJ127
Isotype: IgG1/kappa
Immunogen: Homogenous suspension of 16 week human fetal brain.
Staining pattern: Cell membrane.
Positive control: Tissue sample from neuroblastoma.

APPLICATIONS:
This antibody is designed for the specific localization of human L1-CAM using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.

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