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Kappa Light Chain [Polyclonal]

Ref: AP10060C - Clone: Polyclonal - Host: Rabbit - Method: P - Format: Concentrated
DS  Imagen 1   MSDS  Imagen 2
Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
Antibody to the kappa light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.  Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Polyclonal
Isotype: IgG
Immunogen: Kappa light chains purified from human Bence Jones proteins.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from tonsil.

APPLICATIONS:
This antibody is designed for the specific localization of human kappa light chain using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
Is useful for detecting monoclonality in B cell lymphoproliferative disorders, which provides significant support diagnosis of lymphoma versus lymphoid hyperplasia or other reactive lymphadenitis; as well as in leukemia and plasma cell, plasma cell dysplasias myelomas or plasmacytomas.

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