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CA 125 [SPM111]

Ref: AP10057C - Clone: SPM111 - Host: Mouse - Method: P - Format: Concentrated
DS  Imagen 1   MSDS  Imagen 2
Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
CA125 determinant is present on a mucin-like glycoprotein of high molecular weight. CA125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum. In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland.

Clone: SPM111
Isotype: IgG1
Immunogen: Ovarian cancer cell line.
Staining pattern: Extracellular membrane-associated.
Positive control: Tissue sample from mucinous adenocarcinoma of the ovary, mesothelioma.

APPLICATIONS:
This antibody is designed for the specific localization of human CA 125 using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
CA 125 is a tumor marker commonly associated with ovarian carcinomas; identification of this protein in serum is widely used to monitor this type of tumor. This antigen can also be detected in tumor cells in ovarian carcinomas. It also described the expression of CA 125 in other malignancies such as carcinoma of the seminal vesicles and anaplastic. It is important to note that CA 125 is not found exclusively in malignant tumors.

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