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Actin, Smooth Muscle [1A4]

Ref: AP10010C - Clone: 1A4 - Host: Mouse - Method: P - Format: Concentrated
DS  Imagen 1   MSDS  Imagen 2
Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
This antibody reacts with the alpha isoform of actin from muscle origin, specifically to smooth muscle. It doesn´t show any cross-reactivity with skeletal muscle actin and cardiac muscle as well as other epithelial and mesenchymal cells. Neither reacts with other components of the cytoskeleton.
 
Clone: 1A4
Isotype: IgG2a/kappa.
Immunogen: N-terminal decapeptide of alpha isoform smooth muscle actin, acetylated at the amino-terminus.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from smooth muscle, leiomyoma, leiomyosarcoma or blood vessels.

APPLICATIONS:
This antibody is designed for the specific location of the human protein smooth muscle actin by IHC techniques in buffered formalin-fixed tissues and paraffin embedded.
This antibody provides a useful tool for studying the intracellular distribution of actin and its role in the contractile system.

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